What kind of anti-ischemic medications would cause dilation of the coronary vessels?

Nitrates are a class of anti-ischemic medications that cause dilation of the coronary vessels by relaxing the smooth muscle in the vessel walls. They are commonly used in the management of angina pectoris and acute coronary syndromes. The mechanism of action involves the conversion of nitrates to nitric oxide in the body, which enhances vasodilation. This effect increases blood flow to the heart muscle, thereby alleviating ischemic symptoms.

By improving blood flow through dilation of the coronary arteries, nitrates reduce myocardial oxygen demand and improve oxygen supply, which is crucial for patients with coronary artery disease or those experiencing angina. Other options mentioned do not have a direct effect on the dilation of coronary vessels: platelet glycoprotein medications and anti-platelet drugs primarily focus on preventing clot formation, and aminoglycosides are antibiotics with no role in vascular dilation.